SSPA 2012 PROGRAM

Abstracts can be visualized by clicking on the lecture's title.

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June 10, 2012
16.00-18.00 Registration
18.00-18.15 Opening ceremony

18.15-19.15


Opening lecture, Prof. Bernard Testa, University Hospital Centre, Lausanne, Switzerland
"The Biochemistry of Drug Metabolism; Which are the important Enzymes and Reactions?"
19.15-21.00 Welcome cocktail
 
June 11, 2012
  I session - Pharmacokinetic parameters in drug development
9.00-10.30

Dr Ugo Zanelli, Siena Biotech, Siena, Italy
"Drug development: Determination of pharmacokinetic parameters' an introduction"

10.30-10.45 Coffee break
10.45-12.00 Tutorial, Dr Claus Andersen, Siena Biotech, Siena, Italy
"Pharmacokinetic parameters in drug development tutorials"
12.00-13.20 Lunch
13.20-14.45 PhD thesis dissertations
  II session - In silico prediction of ADMET properties 
14.45-15.45 Dr Antonius Ter Laak, Bayer HealthCare Pharmaceuticals, Berlin, Germany
"In silico ADMET: predicting pharmacokinetic and toxicological properties in drug research and development"
 
15.45-16.00 Coffee break
16.00-16.45 Dr Candida Manelfi, S-IN Soluzioni Informatiche Srl, Vicenza, Italy
"ADMET in silico modelling in drug development"
16.45-17.45

Dr Candida Manelfi, S-IN Soluzioni Informatiche Srl, Vicenza, Italy.
Tutorial: "How ADMET and physicochemical properties can be predicted and used in drug development"

 
June 12, 2012
  III session - In vitro determination of early-ADMET properties
9.00-10.30 Dr Giulio Massimo Dondio, Nikem Research srl, Baranzate, Italy
"eADMET in vitro assays in multiparametric lead optimization: advantages and caveats"
10.30-10.45 Coffee break
10.45-11.45 Prof. Giorgio Grosa, University of Oriental Piedmont, Novara, Italy
"Chemically reactive metabolites in ADMET studies: an analytical challenge"
11.45-12.45

Dr Laurent Geiser, University of Geneva, Switzerland
"Rapid and cost-effective analytical strategies to evaluate CYP-related metabolism and drug-drug interactions of new chemical entities"

12.45-14.00 Lunch
  IV session - In vivo determination of ADMET properties: sample preparation  
14.00-15.00 Dr Veronica Mainini, University of Milano Bicocca – in collaboration with Bruker Daltonics S.r.l.
“Imaging Mass Spectrometry: fundamentals and applications to drug distribution analysis”
15.00-16.30



Prof. Dr Karl-Siegfried Boos, Institute of Clinical Chemistry, Medical Center of the University of Munich, Germany
"Advanced laboratory techniques for the preparation of biofluids. Prior to high performance separation and detection"
16.30-16.45 Coffee break
16.45-17.45



Prof. Dr Karl-Siegfried Boos, Institute of Clinical Chemistry, Medical Center of the University of Munich, Germany
Tutorial: "How to sample, process and clean-up whole blood prior to LC-MS/MS analysis of small molecules"
 
June 13, 2012
9.00-10.00 PhD thesis dissertation
  V session – Biomarkers in drug development
10.00-11.00 Dr Barbara Pioselli, Chiesi Farmaceutici S.p.a, Parma, Italy
"How many types of biomarkers are out there?"
11.00-11.15 Coffee break
11.15-12.30 Dr Coral Barbas, San Pablo-CEU University, Madrid, Spain
"Metabolomics: searching for biomarkers in drug discovery"
12.30-13.30 Dr Antonia Garcia, San Pablo-CEU University, Madrid, Spain
"GC-MS based metabolomics"
13.30-13.45 Closing remarks
13.45-14.45 Farewell lunch


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SSPA 2012
Aula Magna, Polo Scientifico e Didattico di Rimini
via Angherà 22,
Rimini, Italy

SSPA2 2012 Sponsors

 
 
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